Teaching NeuroImages: Marked reduced apparent diffusion coefficient in acute multiple sclerosis lesion

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Teaching NeuroImages: marked reduced apparent diffusion coefficient in acute multiple sclerosis lesion.

J.-M. Bugnicourt, MD P.-Y. Garcia, MD P. Monet, MD B. Bonnaire, MD A. Al Khedr, MD O. Godefroy, MD, PhD A 24-year-old woman presented with sudden right-sided weakness and aphasia. Brain MRI was performed 5 hours after symptoms onset. On diffusion-weighted imaging (DWI), the lesion showed a marked increase in signal intensity and an approximatively 70% mean apparent diffusion coefficient (ADC) d...

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Investigation of apparent diffusion coefficient and diffusion tensor anisotrophy in acute and chronic multiple sclerosis lesions.

BACKGROUND AND PURPOSE The various stages of multiple sclerosis (MS) are characterized by de- and remyelination as well as by inflammation. Diffusion MR imaging is sensitive to tissue water motion, which might correspond to these pathologic processes. Our purpose was to demonstrate differences in apparent diffusion coefficient (ADC) and diffusion tensor anisotropy in acute and chronic MS plaque...

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Reduced apparent diffusion coefficient in neuromyelitis optica-associated optic neuropathy.

I n their excellent review of neuromyelitis optica (NMO), Morrow and Wingerchuk (1) discuss the criteria that distinguish this condition from multiple sclerosis. Here, we describe diffusion-weighted magnetic resonance imaging (DWI) of the optic nerve in a patient with NMO-associated optic neuropathy. A 21-year-old man developed vision loss in the right eye that was diagnosed as optic neuritis. ...

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Segmentation of Ischemic Lesion from Diffusion Weighted MRI and MR Apparent Diffusion Coefficient Maps

The utility of diffusion-weighted MRI (DWI) in the assessment of acute ischemic stroke is now becoming well-established. The quantitative evaluation of the lesion is however problematic because of the lower resolution of clinical images in the context of extreme emergency. We have developed a new segmentation technique to extract the ischemic areas from standard, clinical DWI image volumes. Tho...

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Teaching NeuroImages: Acute Parinaud syndrome.

An 82-year-old man with atrial fibrillation, nonadherent to rivaroxaban, presented with sudden bilateral ptosis. Examination demonstrated bilateral ptosis (figure 1), pupils midline, fixed midsize, not reactive to light but constricting to accommodation, impaired vertical eye movements, paresis of superior greater than inferior rectus, and upgaze convergence nystagmus. MRI showed infarction of ...

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ژورنال

عنوان ژورنال: Neurology

سال: 2010

ISSN: 0028-3878,1526-632X

DOI: 10.1212/wnl.0b013e3181df09f7